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Daniel Sharman
as
Lorenzo de' Medici
Aurora Ruffino
as
Bianca de' Medici
Sebastian De Souza
as
Sandro Botticelli
Alessandra Mastronardi
as
Lucrezia Donati
Synnøve Karlsen
as
Clarice Orsini
Annabel Scholey
as
Contessina de' Medici
Sarah Parish
as
Lucrezia de' Medici (older)
Callum Blake
as
Carlo de' Medici
Bradley James
as
Giuliano de' Medici
Guido Caprino
as
Marco Bello
Raoul Bova
as
Pope Sixtus IV
Richard Madden
as
Cosimo de' Medici
Alessandro Sperduti
as
Piero de' Medici
Valentina Bellè
as
Lucrezia de' Medici
Ken Bones
as
Ugo Bencini
Brian Cox
as
Guadagni
Tatjana Nardone
as
Emilia
Stuart Martin
as
Lorenzo
Matteo Martari
as
Francesco de' Pazzi
Sean Bean
as
Jacopo de' Pazzi
Francesco Montanari
as
Girolamo Savonarola
Johnny Harris
as
Bruno Bernardi
Lex Shrapnel
as
Rinaldo Albizzi
Eugenio Franceschini
as
Ormando Albizzi
Daniel Caltagirone
as
Pazzi
Matilda Anna Ingrid Lutz
as
Simonetta Vespucci
Toby Regbo
as
Tommaso Peruzzi
Michael Schermi
as
Ricciardo
Filippo Nigro
as
Luca Soderini
Dustin Hoffman
as
Giovanni de' Medici
Jack Roth
as
Girolamo Riario
Sarah Felberbaum
as
Maddalena
Alessandro Preziosi
as
Brunelleschi
Valentina Cervi
as
Alessandra Albizzi
David Bamber
as
Pope Eugenius IV
Frances Barber
as
Piccarda
Fortunato Cerlino
as
Bredani
Valentina Carnelutti
as
Maria Tarugi
Marco Zingaro
as
Matteo
Gerolamo Alchieri
as
Maso Degli Albizzi
Andrea Tidona
as
Pope Martin V
Andrea Bruschi
as
Andreas di Cecco
Anthony Howell
as
Francesco Sforza
Giusy Buscemi
as
Rosa
Marco Quaglia
as
Tancredi
Giorgio Caputo
as
Malavolti
Alessandro Cremona
as
Ferzetti
Julian Sands
as
Piero de' Medici (older)
Ben Starr
as
Donatello
David Sturzaker
as
Ezio Contarini
James Murray
as
Dodge Foscari
Roberto Accornero
as
Massimo Contarini
Andrea Bosca
as
Sanuto
Luigi Diberti
as
Cavalcanti
Francesco Castiglione
as
Mercenary #1
Miriam Leone
as
Bianca
Steven Waddington
as
Cossa
Fabrizio Matteini
as
Cardinal Mosca
Alessandro Piavani
as
Bertolo
Roberto Trifiro
as
Cardinal Orsini
David Bradley
as
Bardi
Andy Luotto
as
Sandro Tarugi
Justin Avoth
as
Bishop Viteleschi
Lorenzo Pedrotti
as
Young Cardinal