Season 1
Episode: 1x01 | Airdate: Jul 9, 2012
An offbeat neuroscience professor suffering from paranoid schizophrenia works with the FBI to crack intricate cases in this crime drama. In the series premiere, the professor zeros in on the death of a pharmaceutical executive.
Episode: 1x02 | Airdate: Jul 16, 2012
Pierce is enlisted to help crack the case of a murdered mail-order bride. A twist marks the investigation when it's discovered the prime suspect suffers from an unusual condition. Elsewhere, Moretti is drawn to a handsome new professor.
Episode: 1x03 | Airdate: Jul 23, 2012
Pierce and Moretti spring into action when a serial killer from 1986 returns and begins murdering again. Moretti receives advice about the case from her father, who investigated the original killing spree.
Episode: 1x04 | Airdate: Jul 30, 2012
Pierce scrambles to crack a coded newspaper message left by someone possibly connected to a murder.
Episode: 1x05 | Airdate: Aug 6, 2012
Pierce and Moretti investigate the murder of a young man who was a member of a cult. Elsewhere, Pierce scores a university award for his research.
Episode: 1x06 | Airdate: Aug 20, 2012
Pierce is enlisted to help the FBI investigate the slaying of a therapist. Elsewhere, Moretti inches closer to Professor Hathaway; and Haley uses Pierce as a pawn to get funding for a new building.
Episode: 1x07 | Airdate: Aug 27, 2012
Pierce investigates a case revolving around a schizophrenic. Meanwhile, Moretti tries to impress her new FBI boss.
Episode: 1x08 | Airdate: Sep 3, 2012
Pierce and Moretti investigate the slaying of a female college student, but the case soon forces Pierce to face truths from his past. Meanwhile, Moretti reconsiders her relationship with Dr. Hathaway.
Episode: 1x09 | Airdate: Sep 10, 2012
A conspiracy theory swirls about an effort to cover up the murder of a senator. Pierce is on the case, but he begins to suspect that seemingly trustworthy people are plotting against him.
Episode: 1x10 | Airdate: Sep 17, 2012
New evidence emerges that gives credibility to Pierce's conspiracy theory. Meanwhile, Pierce is forced to confront truths about Natalie.
Season 2
Episode: 2x01 | Airdate: Jun 25, 2013
Agent Kate Moretti asks Dr. Daniel Pierce to determine the mental competency of a man being retried for murder. But the trial takes a shocking and unexpected turn when Pierce's findings question whether the person standing trial is the same person he was six years ago. Meanwhile, Moretti is unpleasantly surprised to discover that the Assistant U.S. Attorney prosecuting the case is her soon-to-be-ex-husband Donnie Ryan.
Episode: 2x02 | Airdate: Jul 2, 2013
Pierce and Moretti take on an extraterrestrial case when a woman reports that aliens have abducted her husband. When Pierce and Moretti arrive to investigate, however, they make a startling discovery. Meanwhile, things heat up between Pierce and his real-life girlfriend, Caroline, but his relationship could be jeopardized if he can't get his imaginary girlfriend, Natalie, out of his mind.
Episode: 2x03 | Airdate: Jul 9, 2013
When a series of bizarre public murders occur, Pierce realizes that the killer is trying to send a message about inattentional blindness, but Donnie doubts this theory. Pierce has a trick up his sleeve that can prove his point, and they must scramble to piece together the clues before the clever killer can make any more examples out of innocent victims.
Episode: 2x04 | Airdate: Jul 16, 2013
Pierce accepts an invitation to work on a case from a renowned environmental activist concerning a chain of abnormal neurological reactions in a group of young girls. However, upon examining the girls, Pierce discovers that a dark secret is at the root of their ailments. Meanwhile, Moretti questions Pierce's motives in working on a case without her.
Episode: 2x05 | Airdate: Jul 23, 2013
Pierce and Morretti plunge into virtual reality to solve the murder of Kurt Simpson, a man who spent most of his time in a massive multiplayer online game called Caleidoscope. After creating an avatar of himself to investigate the crime, Pierce struggles more than ever to distinguish between reality and fantasy.
Episode: 2x06 | Airdate: Jul 30, 2013
New brain device to control tremors seems to have a defect that turns out to be far more serious than a technical malfunction, and Pierce partners with Donnie to investigate. Their unlikely alliance is tested when the case escalates to murder. Meanwhile, Lewicki learns a valuable lesson about dating.
Episode: 2x07 | Airdate: Aug 6, 2013
When Moretti receives a deathbed confession about the hit-and-run murder of a teenager from 1992, she calls on Pierce to determine the ailing man's credibility. The case becomes complicated, however, when the alleged killer's physician, Dr. Hutchins, reveals that his patient's tumor has mysteriously disappeared. Pierce and Moretti must dig deeper into the past to uncover the truth behind a shocking series of apparent homicides.
Episode: 2x08 | Airdate: Aug 13, 2013
Pierce investigates a gruesome stabbing at a psychiatric hospital. Guided by his hallucination of Sigmund Freud, Pierce becomes convinced the hospital is full of dark secrets.
Episode: 2x09 | Airdate: Aug 20, 2013
Donnie tries to help a war hero suffering from a neurological disorder, but what starts out as a good deed ends up having major implications. Meanwhile, Pierce gets an unexpected surprise when a fling from his past shows up.
Episode: 2x10 | Airdate: Aug 27, 2013
Morretti faces criminal charges after taking things into her own hands while working on a dangerous case. Pierce and Donnie strive to clear her name, but as conflicting evidence builds, even Kate begins to question her own innocence.
Episode: 2x11 | Airdate: Feb 25, 2014
With the help of his hallucination, Hall of Famer Mordecai "Three Finger" Brown, Pierce fights for an autistic teen under interrogation for murder. Meanwhile, Dean Haley turns on the charm in order to convince a neuroscience prodigy to attend CLMU.
Episode: 2x12 | Airdate: Mar 4, 2014
Pierce and Lewicki are caught off guard when Lewicki's brother Kenny shows up unannounced. In an unwelcome turn of events, Kenny is named the key suspect in a homicide case, leaving Pierce torn between helping a friend and serving justice. Meanwhile, Lewicki is approached with a tantalizing offer that makes him question Pierce's loyalty to him.
Episode: 2x13 | Airdate: Mar 11, 2014
Tensions arise between the CIA and FBI after Pierce receives a tip that the CIA might be assassinating U.S. citizens. Things become more complicated when one of Pierce's close friends is murdered. Meanwhile, Moretti tries to overcome her trust issues with Donnie.
Episode: 2x14 | Airdate: Mar 18, 2014
Pierce's mental stability is questioned and his job threatened when he is accused of stalking his ex-girlfriend, Caroline Newsome. As the situation escalates, Moretti works to find the real stalker with help from a visiting inspector from Canada.
Season 3
Episode: 3x01 | Airdate: Jun 17, 2014
Dr. Daniel Pierce's picture-perfect new life in Paris is suddenly turned upside down after he is approached by the FBI legat to help with a dangerous international case. Meanwhile, his assistant Max Lewicki and Dean Paul Haley plot to get Pierce to return to Chicago.
Episode: 3x02 | Airdate: Jun 24, 2014
When a prosecutor mysteriously drops dead in the middle of a courtroom, Pierce and Moretti go on the hunt for a killer. Meanwhile, Moretti and Donnie make some decisions about their future.
Episode: 3x03 | Airdate: Jul 1, 2014
After a young victim with a developmental disorder is taken hostage in a bank robbery, Moretti brings in Pierce to interview the boy. When they finally track down the culprits, they discover the case is about much more than money. Meanwhile, Pierce's estranged father James pays him a visit.
Episode: 3x04 | Airdate: Jul 8, 2014
Moretti calls on Pierce to examine Elena Douglas, a woman who has confessed to murder and claims to be possessed by the Devil. Meanwhile, Donnie and Moretti's wedding plans hit a bump in the road.
Episode: 3x05 | Airdate: Jul 15, 2014
When renowned neuroscientist Landon Jennings is found dead, Moretti and Pierce must figure out how someone could have gained access to his impenetrable study in order to kill him. Lewicki finds himself with twice the work when Pierce's father James moves in with them.
Episode: 3x06 | Airdate: Jul 22, 2014
When an infant is reported stolen, Moretti hunts down the kidnapper and makes a very bizarre discovery. As Pierce and Moretti investigate a related murder, they find that there might be another child out there who needs their help. Meanwhile, Donnie and Moretti discuss their future together when Donnie looks into buying a house in the suburbs. Featuring guest star Jeff Branson.
Episode: 3x07 | Airdate: Jul 29, 2014
After Pierce witnesses a gallery owner die during a seizure caused by a video installation, he convinces Moretti that it was actually a murder. Their search for the killer puts them in the middle of a brazen art heist. As Pierce works on the case, he is forced to re-examine his relationship with Natalie. Featuring guest star Francesca Eastwood.
Episode: 3x08 | Airdate: Aug 5, 2014
After a missing FBI agent turns up dead, Pierce is forced to face the one case he was never able to solve. When they discover that the killer is still out there, Pierce agrees to help Moretti, against the wishes of his therapist, Dr. Rosenthal, who believes it will only exacerbate Pierce's condition.
Episode: 3x09 | Airdate: Aug 12, 2014
Donnie and Moretti are caught in the crossfire when a sniper shoots up the lobby of the Federal Building. When Pierce determines that the shooter is afraid of Extreme Low Frequency radio waves, he and Moretti take a trip to the Quiet Zone in Virginia, where they think the shooter is hiding out. Meanwhile, an alluring woman named Shelby Buchanan courts Donnie to run for political office.
Episode: 3x10 | Airdate: Aug 19, 2014
When Donnie finds himself in a compromising situation, he calls Pierce for help. As the evidence begins to stack against Donnie, Pierce and Moretti struggle with their own fears and doubts, as they work to solve the case. During the chaos, Pierce must deal with his father after he assaults someone at the assisted living facility.
Episode: 3x11 | Airdate: Feb 17, 2015
After Dr. Daniel Pierce suffers a traumatic injury, his father, James, and his friend Paul Haley have to make a difficult choice on whether to allow Pierce to undergo a high-risk surgery. Meanwhile, Pierce works to solve a different kind of murder case that has him questioning everything he sees and hears.
Episode: 3x12 | Airdate: Feb 24, 2015
When the owners of a meat company are brutally murdered, Agent Kate Moretti goes undercover to investigate an animal rights group suspected of foul play. Meanwhile, as Pierce helps solve the case, he considers making a deeply personal confession to Kate.
Episode: 3x13 | Airdate: Mar 3, 2015
Pierce and Moretti undercover an international scandal while investigating the murders of a Bangladeshi diplomat and a Chicago reporter. Distracted by the case, Moretti struggles with preparations for her upcoming wedding to Donnie and turns to Pierce for help.
Episode: 3x14 | Airdate: Mar 10, 2015
After a student is found murdered, Pierce tries to find the killer while defending the victim's boyfriend, who is believed to be mentally ill and guilty of the crime. Meanwhile, Pierce must confront his feelings as Kate and Donnie prepare for their wedding day.
Episode: 3x15 | Airdate: Mar 17, 2015
When Moretti goes missing the day of her wedding, Pierce and Donnie set off in pursuit of the runaway bride. They soon learn that Kate has been abducted by a dangerous person from Pierce's own past. Now, Pierce and Donnie must risk everything to save Moretti before it's too late.